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Use of Biomarkers to Guide Decisions on Adjuvant Systemic Therapy for Women With Early-Stage Invasive Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline.
After a median follow-up of 35 months, there was a 65% relative risk reduction in the annual incidence of invasive breast cancer following treatment with exemestane (0.
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Angioedema: Patients who take an angiotensin-converting enzyme (ACE) inhibitor medicine during treatment with AFINITOR are at a possible increased risk for a type of allergic reaction called angioedema.
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Hormonal therapy may be given to block these hormones from stimulating tumor growth.
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Of extreme importance will be the woman's decision whether the entire breast is to be removed, or only a part of it - and that is usually much more a personal choice than a medical asessment.
The cardiovascular side effects of Aromasin can include high blood pressure as mentioned above; however, baring an underlying issue, genetic predisposition or generally unhealthy lifestyle most should not have a problem.
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Patients on exemestane plus OFS reported more vaginal dryness, greater loss of sexual interest, and difficulties becoming aroused than did patients on tamoxifen plus OFS; these differences persisted over time.
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The safety profile of exemestane shares some side effects with tamoxifen (hot flashes and arthralgia), but is not associated with an increased risk of endometrial cancer or thromboembolic events.
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Therefore, it appears that neurobehavioral problems have the largest effect on QOL of patients with tumors and their families.
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If breast cancer does recur or a new primary cancer is found, oncologists may be able to approach treatment with the assumption that it's a curable situation.
The best outcome in the “new normal” for patients is a lifestyle that has changed to a healthier one and an attitude that has changed to one of ongoing appreciation where each day is viewed as a gift.
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If you've had one first-degree female relative (sister, mother, daughter) diagnosed with breast cancer, your risk is doubled.
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Magnitude of Effect: Nearly all women experience some sleep disturbances, mood changes, hot flashes, and bone demineralization, but the severity of these symptoms varies greatly.
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The results of the proposed extension to the companion study will help us understand the long term effects and long term safety of exemestane on bone health in postmenopausal women at risk of developing breast cancer.
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This is why it is most important to report to your doctor early any instance of unusual vaginal bleeding.
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The side effects are often not addressed adequately, if at all, by oncologists.
CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug.
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DHEA might increase estrogen in the body and decrease the effectiveness of letrozole (Femara) for treating cancer.
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Because of the prevalence of abnormal or unexpected findings in asymptomatic patients, mri of the spine and computed tomography should be reserved for patients targeted for surgical intervention or those in whom tumour or infection is a concern.
Secondary objectives of the study included the evaluation of clinical and pathologic response of primary breast cancer to preoperative chemotherapy, the determination of the downstaging effect of preoperative chemotherapy in the axillary nodes, and the determination of whether preoperative chemotherapy increases the rate of breast-conserving surgery.
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In a clinical trial, measuring the EFS is one way to see how well a new treatment works.
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Aromatase Inhibitors in the Adjuvant Treatment of Postmenopausal Women with Early Breast Cancer: Putting Safety Issues into Perspective.
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It is a heinous drug, but according to my oncologist, a life saver, so I will continue to take it.
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DM) have been associated involvement of other organs (heart, lung, and joints) and complications of therapy (infections, osteonecrosis, and osteoporotic compression fractures) that affect disability status aside from the proximal weakness that characterizes the syndrome.
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According to the NCCN Clinical Practice Guidelines in Oncology: Prostate Cancer (available at ), long-term ADT is used for locally advanced, recurrent, and metastatic prostate cancer.
If you or someone you love has been diagnosed with breast cancer, the questions may seem endless.
Removing the ovaries lowers the risk of breast cancer because the ovaries are the main source of estrogen in a premenopausal woman's body.
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In recent years, a class of chemotherapy drugs called the taxanes has been widely used in the treatment of breast cancer.
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Management with appropriate medical therapy is recommended.
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