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However, evidence suggests that candidiasis occurs with increased frequency in adults during the first 2 months after initiation of HAART, except for candidal eosophagitis ( 301).

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Complementary and alternative therapy (CAT) use and highly active antiretroviral therapy (HAART): current evidence in the literature, 2000-2009.

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Initial approval was based on evidence of a short-term survival advantage over placebo when zidovudine was given to patients with advanced HIV disease.

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Consider PCP in patients with severe pneumonia or more advanced HIV disease.

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Assessment of topical microbicides to prevent HIV-1 transmission: concepts, testing, lessons learned.

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The clinical effectiveness and cost-effectiveness of screening for anal squamous intraepithelial lesions in homosexual and bisexual HIV-positive men.

To assess accuracy of pill count data to monitor adherence, detectable tenofovir in plasma was compared with clinic-based pill count data.

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Bioavailability is improved with the use of valacyclovir, the valyl ester formulation of acyclovir.

Telaprevir: May increase the serum concentration of Tenofovir Disoproxil Fumarate.

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IM) daily in a single dose for 10 days ( BII).

Taking Complera with food is important to help get the right amount of medicine in your body.

Options are very minimal and cannot combo with other drugs.

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Participants were instructed to take a loading dose of two pills of TDF-FTC or placebo with food 2 to 24 hours before sex, followed by a third pill 24 hours after the first drug intake and a fourth pill 24 hours later.

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Treatment with Complera should be suspended in any patient who develops clinical or laboratory findings suggestive of lactic acidosis or pronounced hepatotoxicity (which may include hepatomegaly and steatosis even in the absence of marked transaminase elevations).

The population used for analysis of ALT normalization included only subjects with ALT above ULN at baseline.

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R-(active), S- and total methadone exposures were equivalent when dosed alone or with VIREAD.

Significant renal, cardiovascular, pulmonary, or neurological disease.

Virologic response is highly correlated with the inhibitory quotient (IQ), defined as the trough concentration divided by the inhibitory concentration of the drug (eg, the IC 50 in a standardized assay).

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Some of this kidney dysfunction will be related to tenofovir toxicity, and some will not.

Tenofovir disoproxil fumarate is an acyclic nucleoside phosphonate diester analog of adenosine monophosphate.

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In lab experiments with cells of the immune system and TAF, researchers have found that TAF is quickly converted into the antiviral form of the drug, tenofovir.

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Zanamivir has occasionally been given IV to treat critically ill patients with influenza.

Perceived Risk Among Human Immunodeficiency Virus Serodiscordant Couples in East Africa Taking Oral Pre-Exposure Prophylaxis.

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Dear healthcare provider letter: high rate of virologic failure in patients with HIV infection treated with once-daily triple NRTI regimen containing didanosine, lamivudine, and tenofovir.

The drug regimen involves 3 or 4 drugs being taken together so if the virus becomes resistant to 1 of the medications you take, there are a few “back-up” drugs to keep fighting the virus.

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This sequence is then compared with that of a drug-sensitive (“wild-type”) strain of HIV, and differences (mutations) present in the specimen sequence are noted.

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The need for multipurpose prevention technologies in sub-Saharan Africa.

Interferons as Therapy for Viral and Neoplastic Diseases: From Panacea to Pariah to Paragon.

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See Specific Drugs and Laboratory Tests under Interactions.

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TRUVADA group and 83 subjects in the placebo group who became infected with HIV-1 during the trial.

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Serologic tests such as antinuclear antibody (ANA) and antineutrophil cytoplasmic antibody (ANCA) assays are of limited utility because false-positive serologies are more common in HIV-infected patients than in HIV-uninfected patients.

Effect of community-based voluntary counselling and testing on HIV incidence and social and behavioural outcomes (NIMH Project Accept; HPTN 043): a cluster-randomised trial.

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During the trial period, patients who started ART early and those who deferred and eventually started ART had similar rates of loss to follow-up, attendance at scheduled visits, and virologic success at 24 months.

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